Description

This course provides students with knowledge of physical and chemical principles essential for the design and formulation of pharmaceutical products. Students are introduced to the fundamental concepts of states of matter, phase equilibrium, solubility, partition coefficient, diffusion, dissolution, surface and interfacial phenomena, surface active agents, and its application in pharmacy. In addition to the rheological behavior of dosage forms and its application in pharmaceutical sciences and pharmacy practice.

Program

PharmD Clinical

Objectives

• By the end of the course the student should be able to: a1. Define solid state properties including amorphous and crystalline forms, fundamental concepts of solubility, diffusion, dissolution rate and interfacial phenomena among others. a2. Describe the factors affecting solubility of solutes (solid, liquid and gas) in solvents, their diffusion through a membrane, their dissolution, in addition to interfacial properties. a3. List different types of crystal structures and micelles and their application in pharmacy. a4. Describe different processes applications in pharmaceutical sciences and pharmacy practice. Intellectual Skills At the end of the course the student should be able to: b1. Calculate surface and interfacial tension, diffusion, partition and spreading coefficients among others. b2. Apply Fick’s law of diffusion and Noyes Whitney equation showing their pharmaceutical applications. b3. Classify surface active agents relative to their applications in pharmacy. b4. Differentiate between rheograms of Newtonian and non-Newtonian fluids. Professional and Practical skills At the end of the course the student should be able to: c1. Perform basic calculations related to solubility and dissolution rate tests, interfacial and rheological properties of materials among others. c2 Interpret the experimental results and represent the data in a tabular and/or graphical form. c3. Design a scientific report. General and Transferable skills At the end of the course the student should be able to: d1. Communicate effectively during interactive modules. d2. Work under stress within certain limits and manage time properly during written essay type exams and timed multiple choice questions. d3. Verify the skills of data presentation and self-learning using text book and internet.