Basic Pharmacology (1 hr Lecture+1 hr Practical)

  • College of Pharmacy |

Description

This course provides the students with the knowledge of the basic principles of pharmacology, pharmacodynamics (general and molecular aspects) and pharmacokinetics. Concepts of agonism, antagonism, and modulation of receptor activity are reviewed together with a general overview of the different potential interventions with the function of various neurotransmitters and humoral mediators as examples of mechanisms of drug action. Practical exercises aim to help students apply this acquired knowledge using selected in-vitro animal models as well as simulation techniques.

Program

Bachelor of Pharmacy - PharmD

Objectives

  • 1.1 Explain the processes and basic parameters of drug absorption, distribution, metabolism, and excretion.

    1.2 Interpret dose-response curves and distinguish agonism, antagonism, potency, and efficacy.

    1.3 Explain the principal neurotransmitters and pharmacological control of the autonomic nervous system.

    2.1 Calculate basic pharmacokinetic parameters from provided data.

    2.2 Apply pharmacokinetic principles in simulation models and simple dosage-regimen problems.

    2.3 Perform pharmacology laboratory activities safely and ethically, following approved procedures for handling and disposal of biological and pharmaceutical materials.

    3.1 Relate pharmacokinetic and pharmacodynamic principles to the safe and rational use of medicines.

    3.2 Explain how mechanisms of action, contraindications, adverse drug reactions, and drug interactions influence medicine use.

    3.3 Identify common adverse drug reactions and propose appropriate monitoring measures in basic cases.

    4.1 Analyze basic pharmacological cases using critical-thinking and problem-solving skills.

    4.2 Communicate pharmacological information clearly in written and oral formats.

    4.3 Work effectively and responsibly as a member of a team during practical activities.

    4.4 Demonstrate self-directed learning by locating and using appropriate scientific resources for continuous professional development.

Textbook

Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J., & Henderson, G. (2016). Rang and Dale's Pharmacology (8th ed.). Elsevier Churchill Livingstone.

Course Content

content serial Description
1Introduction to Pharmacology. (Lecture)
1Introduction to pharmacology laboratory and types of experiments. (Practical)
2Pharmacodynamics: general aspects. (Lecture)
2Autonomic nervous system introduction; neurotransmitter concepts and OBsim. (Practical)
3Pharmacodynamics: molecular aspects (1). (Lecture)
3Different types of receptors. (Practical)
4Pharmacodynamics: molecular aspects (2). (Lecture)
4Dose-response curves for different drugs and measurement of parameters. (Practical)
5Pharmacokinetics: introduction. (Lecture)
5Pharmacokinetics. (Practical)
6Pharmacokinetics: absorption and distribution. (Lecture)
6Autonomic nervous system disorders: dysautonomia.(Practical)
7Pharmacokinetics: metabolism and excretion. (Lecture)
7Autonomic nervous system disorders: dysautonomia + quiz. (Practical)
8Autonomic nervous system pharmacology (1). (Lecture)
8Effect of indirectly acting stimulant drugs on isolated rabbit intestine: acetylcholine. (Practical)
9Autonomic nervous system pharmacology (2). (Lecture)
9Effect of indirectly acting stimulant drugs on isolated rabbit intestine: acetylcholine. (Practical)
10Drugs acting on the parasympathetic nervous system (1).(Lecture)
10Reversible competitive antagonism of atropine and acetylcholine on isolated rabbit intestine. (Practical)
11Drugs acting on the parasympathetic nervous system (2).(Lecture)
11Effect of directly acting stimulant drug BaCl2 on isolated rabbit intestine. (Practical)
12Drugs acting on the parasympathetic nervous system (3).(Lecture)
12Differentiate between effects of directly and indirectly acting drugs on isolated rabbit intestine. (Practical)
13Drugs acting on the sympathetic nervous system (1). (Lecture)
13Differentiate between effects of directly and indirectly acting drugs on isolated rabbit intestine + quiz. (Practical)
14Drugs acting on the sympathetic nervous system (2). (Lecture)
14Kortext open-book activity . (Practical)
15Drugs acting on the sympathetic nervous system (3).(Lecture)
15Kortext open-book activity. (Practical)

Markets and Career

  • Generation, transmission, distribution and utilization of electrical power for public and private sectors to secure both continuous and emergency demands.
  • Electrical power feeding for civil and military marine and aviation utilities.
  • Electrical works in construction engineering.

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