- Degree Bachelor
- Code: PD226
- Credit hrs: 2
- Prequisites: PD222
This course provides the students with the knowledge of the basic principles of pharmacology, pharmacodynamics (general and molecular aspects) and pharmacokinetics. Concepts of agonism, antagonism, and modulation of receptor activity are reviewed together with a general overview of the different potential interventions with the function of various neurotransmitters and humoral mediators as examples of mechanisms of drug action. Practical exercises aim to help students apply this acquired knowledge using selected in-vitro animal models as well as simulation techniques.
Bachelor of Pharmacy - PharmD
1.1 Explain the processes and basic parameters of drug absorption, distribution, metabolism, and excretion.
1.2 Interpret dose-response curves and distinguish agonism, antagonism, potency, and efficacy.
1.3 Explain the principal neurotransmitters and pharmacological control of the autonomic nervous system.
2.1 Calculate basic pharmacokinetic parameters from provided data.
2.2 Apply pharmacokinetic principles in simulation models and simple dosage-regimen problems.
2.3 Perform pharmacology laboratory activities safely and ethically, following approved procedures for handling and disposal of biological and pharmaceutical materials.
3.1 Relate pharmacokinetic and pharmacodynamic principles to the safe and rational use of medicines.
3.2 Explain how mechanisms of action, contraindications, adverse drug reactions, and drug interactions influence medicine use.
3.3 Identify common adverse drug reactions and propose appropriate monitoring measures in basic cases.
4.1 Analyze basic pharmacological cases using critical-thinking and problem-solving skills.
4.2 Communicate pharmacological information clearly in written and oral formats.
4.3 Work effectively and responsibly as a member of a team during practical activities.
4.4 Demonstrate self-directed learning by locating and using appropriate scientific resources for continuous professional development.
Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J., & Henderson, G. (2016). Rang and Dale's Pharmacology (8th ed.). Elsevier Churchill Livingstone.
| content serial | Description |
|---|---|
| 1 | Introduction to Pharmacology. (Lecture) |
| 1 | Introduction to pharmacology laboratory and types of experiments. (Practical) |
| 2 | Pharmacodynamics: general aspects. (Lecture) |
| 2 | Autonomic nervous system introduction; neurotransmitter concepts and OBsim. (Practical) |
| 3 | Pharmacodynamics: molecular aspects (1). (Lecture) |
| 3 | Different types of receptors. (Practical) |
| 4 | Pharmacodynamics: molecular aspects (2). (Lecture) |
| 4 | Dose-response curves for different drugs and measurement of parameters. (Practical) |
| 5 | Pharmacokinetics: introduction. (Lecture) |
| 5 | Pharmacokinetics. (Practical) |
| 6 | Pharmacokinetics: absorption and distribution. (Lecture) |
| 6 | Autonomic nervous system disorders: dysautonomia.(Practical) |
| 7 | Pharmacokinetics: metabolism and excretion. (Lecture) |
| 7 | Autonomic nervous system disorders: dysautonomia + quiz. (Practical) |
| 8 | Autonomic nervous system pharmacology (1). (Lecture) |
| 8 | Effect of indirectly acting stimulant drugs on isolated rabbit intestine: acetylcholine. (Practical) |
| 9 | Autonomic nervous system pharmacology (2). (Lecture) |
| 9 | Effect of indirectly acting stimulant drugs on isolated rabbit intestine: acetylcholine. (Practical) |
| 10 | Drugs acting on the parasympathetic nervous system (1).(Lecture) |
| 10 | Reversible competitive antagonism of atropine and acetylcholine on isolated rabbit intestine. (Practical) |
| 11 | Drugs acting on the parasympathetic nervous system (2).(Lecture) |
| 11 | Effect of directly acting stimulant drug BaCl2 on isolated rabbit intestine. (Practical) |
| 12 | Drugs acting on the parasympathetic nervous system (3).(Lecture) |
| 12 | Differentiate between effects of directly and indirectly acting drugs on isolated rabbit intestine. (Practical) |
| 13 | Drugs acting on the sympathetic nervous system (1). (Lecture) |
| 13 | Differentiate between effects of directly and indirectly acting drugs on isolated rabbit intestine + quiz. (Practical) |
| 14 | Drugs acting on the sympathetic nervous system (2). (Lecture) |
| 14 | Kortext open-book activity . (Practical) |
| 15 | Drugs acting on the sympathetic nervous system (3).(Lecture) |
| 15 | Kortext open-book activity. (Practical) |
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