- Degree Bachelor
- Code: PD313
- Credit hrs: 3
- Prequisites: PD117
The course introduces the students to define micromeritics, and methods for determining the particle size. The course also aims at providing the students with a broad knowledge on the various types of excipients and additives used in preparation of different solid dosage forms and their effect on dosage form dissolution and in-vitro possible drug/excipients interactions. It also describes the principles and techniques involved in the formulation and manufacturing of solid dosage forms including powders, granules, tablets (chewable, coated, effervescent, buccal and sublingual), capsules (hard and soft gelatin capsule) and multiparticulate systems such as pellets and minitablets. In addition, studying different quality control tests for each dosage form.
Bachelor of Pharmacy - PharmD
1.1 Demonstrate understanding of knowledge of solid dosage forms.
1.2 Utilize the proper pharmaceutical terms like micromeritics (particle size analysis and powder flow) of solid dosage forms preparation, abbreviations, and symbols in pharmacy practice.
1.3 Integrate knowledge from fundamental sciences about various excipients used to handle, design, prepare and assure quality of different formulations of solid pharmaceutical products such as powders, granules, capsules and Tablets
1.4 Identify and critically analyze newly emerging issues influencing pharmaceutical industry.
2.1 Apply the basic requirements of quality control system to evaluate and characterize solid dosage forms.
2.2 Design different solid dosage forms prescriptions.
2.3 Recognize the principles of various instruments and select the proper techniques for synthesis of different solid dosage forms.
2.4Adopt the principles of pharmaceutical calculations of solid preparations.
3.1 Educate and counsel patients about safe and proper use of solid preparations such as dry powder inhalers, effervescent granules, different types of tablets specially OTC preparations.
3.2 Maintain public awareness on social health hazards of drug misuse and abuse.
4.4 Practice independent learning needed for continuous professional development.
4.2 Retrieve and critically analyze information, identify and solve problems, and work autonomously and effectively in a team
4.3 Use new technologies and media to demonstrate effective presentation skills.
4.1 Demonstrate responsibility for team performance and peer evaluation of other team members, and express time management skills.
Allen, L. V. Jr. & McPherson, T. B. Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems. 12th ed. (2023).
| content serial | Description |
|---|---|
| 1 | Introduction to solid dosage forms. (Lecture) |
| 1 | Good compounding practice. (Practical) |
| 2 | Pharmaceutical powder.(Lecture) |
| 2 | Particle size analysis by sieving.(Practical) |
| 3 | Pharmaceutical granules and Effervescent granules.(Lecture) |
| 3 | Particle size analysis by microscope. (Practical) |
| 4 | Quality control testing of powders and granules. (Lecture) |
| 4 | Evaluation of powder flow. (Practical) |
| 5 | Introduction to Capsules. (Lecture) |
| 5 | Bulk and divided powder & Comparison between flow properties of powders and granules (Angle of repose, Carr’s index and Hausner ratio). (Practical) |
| 6 | Hard gelatin Capsules. (Lecture) |
| 6 | Geometric mixing of powders. (Practical) |
| 7 | Soft gelatin Capsules. (Lecture) |
| 7 | Preparation of dusting powder. (Practical) |
| 8 | Tablets and tablets excipients. (Lecture) |
| 8 | Preparation of Carminative (mixing liquids in powders). (Practical) |
| 9 | Tablets’ excipients: Part II. (Lecture) |
| 9 | Preparation of antispasmodic powder (Extracts with powders). (Practical) |
| 10 | Methods of tablet preparation. (Lecture) |
| 10 | Effervescent granules. (Practical) |
| 11 | Overview of tablet coating (Film coating). (Lecture) |
| 11 | Preparation of sodium citrotartarate effervescent granules. (Practical) |
| 12 | Overview of tablet coating (Sugar coating+ compression coating). (Lecture) |
| 12 | Preparation of Ferrous Fumarate effervescent granules. (Practical) |
| 13 | Problems occurred during tablets coating & Quality Control testing of tablets &capsules. (Lecture) |
| 13 | Preparation of Uricosuric effervescent granules. (Practical) |
| 14 | Multi particulate drug delivery system (minitablets/ pellets). (Lecture) |
| 14 | Preparation of tablets by molding technique. (Practical) |
| 15 | Quality Control testing of multi particulate systems. (Lecture) |
| 15 | Students' presentations on selected solid dosage forms prescriptions. (Practical) |
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