Pharmaceutical Dosage Forms III (2 hrs Lecture+1 hr Practical)

  • College of Pharmacy |

Description

The course introduces the students to define micromeritics, and methods for determining the particle size. The course also aims at providing the students with a broad knowledge on the various types of excipients and additives used in preparation of different solid dosage forms and their effect on dosage form dissolution and in-vitro possible drug/excipients interactions. It also describes the principles and techniques involved in the formulation and manufacturing of solid dosage forms including powders, granules, tablets (chewable, coated, effervescent, buccal and sublingual), capsules (hard and soft gelatin capsule) and multiparticulate systems such as pellets and minitablets. In addition, studying different quality control tests for each dosage form.

Program

Bachelor of Pharmacy - PharmD

Objectives

  • 1.1 Demonstrate understanding of knowledge of solid dosage forms.

    1.2 Utilize the proper pharmaceutical terms like micromeritics (particle size analysis and powder flow) of solid dosage forms preparation, abbreviations, and symbols in pharmacy practice.

    1.3 Integrate knowledge from fundamental sciences about various excipients used to handle, design, prepare and assure quality of different formulations of solid pharmaceutical products such as powders, granules, capsules and Tablets

    1.4 Identify and critically analyze newly emerging issues influencing pharmaceutical industry.

    2.1 Apply the basic requirements of quality control system to evaluate and characterize solid dosage forms.

    2.2 Design different solid dosage forms prescriptions.

    2.3 Recognize the principles of various instruments and select the proper techniques for synthesis of different solid dosage forms.

    2.4Adopt the principles of pharmaceutical calculations of solid preparations.

    3.1 Educate and counsel patients about safe and proper use of solid preparations such as dry powder inhalers, effervescent granules, different types of tablets specially OTC preparations.

    3.2 Maintain public awareness on social health hazards of drug misuse and abuse.

    4.4 Practice independent learning needed for continuous professional development.

    4.2 Retrieve and critically analyze information, identify and solve problems, and work autonomously and effectively in a team

    4.3 Use new technologies and media to demonstrate effective presentation skills.

    4.1 Demonstrate responsibility for team performance and peer evaluation of other team members, and express time management skills.

Textbook

Allen, L. V. Jr. & McPherson, T. B. Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems. 12th ed. (2023).

Course Content

content serial Description
1Introduction to solid dosage forms. (Lecture)
1Good compounding practice. (Practical)
2Pharmaceutical powder.(Lecture)
2Particle size analysis by sieving.(Practical)
3Pharmaceutical granules and Effervescent granules.(Lecture)
3Particle size analysis by microscope. (Practical)
4Quality control testing of powders and granules. (Lecture)
4Evaluation of powder flow. (Practical)
5Introduction to Capsules. (Lecture)
5Bulk and divided powder & Comparison between flow properties of powders and granules (Angle of repose, Carr’s index and Hausner ratio). (Practical)
6Hard gelatin Capsules. (Lecture)
6Geometric mixing of powders. (Practical)
7Soft gelatin Capsules. (Lecture)
7Preparation of dusting powder. (Practical)
8Tablets and tablets excipients. (Lecture)
8Preparation of Carminative (mixing liquids in powders). (Practical)
9Tablets’ excipients: Part II. (Lecture)
9Preparation of antispasmodic powder (Extracts with powders). (Practical)
10Methods of tablet preparation. (Lecture)
10Effervescent granules. (Practical)
11Overview of tablet coating (Film coating). (Lecture)
11Preparation of sodium citrotartarate effervescent granules. (Practical)
12Overview of tablet coating (Sugar coating+ compression coating). (Lecture)
12Preparation of Ferrous Fumarate effervescent granules. (Practical)
13Problems occurred during tablets coating & Quality Control testing of tablets &capsules. (Lecture)
13Preparation of Uricosuric effervescent granules. (Practical)
14Multi particulate drug delivery system (minitablets/ pellets). (Lecture)
14Preparation of tablets by molding technique. (Practical)
15Quality Control testing of multi particulate systems. (Lecture)
15Students' presentations on selected solid dosage forms prescriptions. (Practical)

Markets and Career

  • Generation, transmission, distribution and utilization of electrical power for public and private sectors to secure both continuous and emergency demands.
  • Electrical power feeding for civil and military marine and aviation utilities.
  • Electrical works in construction engineering.

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