- Degree Bachelor
- Code: PD426
- Credit hrs: 3
- Prequisites: PD226
. This course provides basics and concepts of toxicology including the mechanism of toxicity, target organ and treatment of toxicity. Toxic groups including heavy metals, toxic gases, animal, plant and marine poisons, pesticides and radiation hazards are covered. Environmental, occupational, reproductive and genetic toxicology as well as drug abuse are included. Postmortem sampling for detection of poisons, methods of detection, interpretation of results and writing of a report are also covered.
Bachelor of Pharmacy - PharmD
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1.1 Recognize the concept of toxicity of xenobiotics & modifying factors
1.2 Define various organ toxicity profiles and antidotal measures
1.3 Recognize hazards of occupational toxicity and other selective toxicities
1.4 Describe different preclinical testings of new drugs toxicity and adverse effects
1.5 Recognize genetic toxicology and toxicity of drugs, gases, heavy metals and poisons
2.1 Differentiate toxicity symptoms, categorize toxic agents and treatment measures
2.2 Estimate short and long-term health hazards of pollutants and toxins
2.3 Relate integrated approaches to scientific problem solving
2.4 Evaluate the design of pre-clinical toxicity screening tests
2.5 Analyze and criticize published information concerning scientific data
3.1 Demonstrate drug toxicities profiles and gross symptoms of poisoning
3.2 Practice identification of poisons
3.3 Use chemicals, reagents and animals and carry out standard laboratory analytical procedures safely
4.1 Communicate clearly by verbal and written means
4.2 Work effectively within a team
4.3 Practice self- learning and demonstrate time management ability
Casarett & Doull's essentials of toxicology. Authors: Curtis D Klaassen; John B Watkins. 3rd edition (2015). Publisher: New York: McGraw-Hill Medical
| content serial | Description |
|---|---|
| 1 | Scope and principles of toxicology, mechanisms of toxicity and Factorial toxicology.(Lecture) |
| 1 | Introduction of Practical Toxicology and Animal Handli.(Tutorial) |
| 2 | Medical toxicology.(Lecture) |
| 2 | Toxicology report sheet and Animal House “Animal Handling”.(Tutorial) |
| 3 | Toxicity of heavy metals.(Lecture) |
| 3 | Poisons acting locally: Acids and caustic alkalis.(Tutorial) |
| 4 | Food toxicology: Food-borne toxins and adverse reactions to food.(Lecture) |
| 4 | Poisons acting systemically and locally and systemically.(Tutorial) |
| 5 | Food toxicology (2): food additives and safety standards.(Lecture) |
| 5 | Poisons acting skeletal muscle and nerve activity.(Tutorial) |
| 6 | Descriptive toxicology: General principles in the assessment of safety of new compounds and LD50 determination.(Lecture) |
| 6 | Hypoxia.(Tutorial) |
| 7 | Descriptive toxicology (2): Acute, subchronic and chronic toxicity tests.(Lecture) |
| 7 | 7th Quiz Theo practical + OSPE.(Tutorial) |
| 8 | Toxicity of chemical warfare agents.(Lecture) |
| 8 | Poisons and their antidotes .(Tutorial) |
| 9 | Toxicity of pesticides: insecticides.(Lecture) |
| 9 | Biocides.(Tutorial) |
| 10 | Toxicity of pesticides (2): rodenticides and herbicides.(Lecture) |
| 10 | Forensic Toxicology.(Tutorial) |
| 11 | Radiation toxicology.(Lecture) |
| 11 | Medical Toxicology. (Tutorial) |
| 12 | Forensic toxicology.(Lecture) |
| 12 | Drug of abuse.(Tutorial) |
| 13 | Occupational toxicology.(Lecture) |
| 13 | 12th Quiz Theo practical +OSPE.(Tutorial) |
| 14 | Mutagenicity and carcinogenesis.(Lecture) |
| 14 | Theoretical Presentations I .(Tutorial) |
| 15 | Genetic and developmental toxicology.(Lecture) |
| 15 | Theoretical Presentations II.(Tutorial) |
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