Toxicology & forensic chemistry (2 hrs Lecture+1 hr Practical)

  • College of Pharmacy |

Description

. This course provides basics and concepts of toxicology including the mechanism of toxicity, target organ and treatment of toxicity. Toxic groups including heavy metals, toxic gases, animal, plant and marine poisons, pesticides and radiation hazards are covered. Environmental, occupational, reproductive and genetic toxicology as well as drug abuse are included. Postmortem sampling for detection of poisons, methods of detection, interpretation of results and writing of a report are also covered.

Program

Bachelor of Pharmacy - PharmD

Objectives

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    1.1 Recognize the concept of toxicity of xenobiotics & modifying factors

    1.2 Define various organ toxicity profiles and antidotal measures

    1.3 Recognize hazards of occupational toxicity and other selective toxicities

    1.4 Describe different preclinical testings of new drugs toxicity and adverse effects

    1.5 Recognize genetic toxicology and toxicity of drugs, gases, heavy metals and poisons

    2.1 Differentiate toxicity symptoms, categorize toxic agents and treatment measures

    2.2 Estimate short and long-term health hazards of pollutants and toxins

    2.3 Relate integrated approaches to scientific problem solving

    2.4 Evaluate the design of pre-clinical toxicity screening tests

    2.5 Analyze and criticize published information concerning scientific data

    3.1 Demonstrate drug toxicities profiles and gross symptoms of poisoning

    3.2 Practice identification of poisons

    3.3 Use chemicals, reagents and animals and carry out standard laboratory analytical procedures safely

    4.1 Communicate clearly by verbal and written means

    4.2 Work effectively within a team

    4.3 Practice self- learning and demonstrate time management ability

Textbook

Casarett & Doull's essentials of toxicology. Authors: Curtis D Klaassen; John B Watkins. 3rd edition (2015). Publisher: New York: McGraw-Hill Medical

Course Content

content serial Description
1Scope and principles of toxicology, mechanisms of toxicity and Factorial toxicology.(Lecture)
1Introduction of Practical Toxicology and Animal Handli.(Tutorial)
2Medical toxicology.(Lecture)
2Toxicology report sheet and Animal House “Animal Handling”.(Tutorial)
3Toxicity of heavy metals.(Lecture)
3Poisons acting locally: Acids and caustic alkalis.(Tutorial)
4Food toxicology: Food-borne toxins and adverse reactions to food.(Lecture)
4Poisons acting systemically and locally and systemically.(Tutorial)
5Food toxicology (2): food additives and safety standards.(Lecture)
5Poisons acting skeletal muscle and nerve activity.(Tutorial)
6Descriptive toxicology: General principles in the assessment of safety of new compounds and LD50 determination.(Lecture)
6Hypoxia.(Tutorial)
7Descriptive toxicology (2): Acute, subchronic and chronic toxicity tests.(Lecture)
77th Quiz Theo practical + OSPE.(Tutorial)
8Toxicity of chemical warfare agents.(Lecture)
8Poisons and their antidotes .(Tutorial)
9Toxicity of pesticides: insecticides.(Lecture)
9Biocides.(Tutorial)
10Toxicity of pesticides (2): rodenticides and herbicides.(Lecture)
10Forensic Toxicology.(Tutorial)
11Radiation toxicology.(Lecture)
11Medical Toxicology. (Tutorial)
12Forensic toxicology.(Lecture)
12Drug of abuse.(Tutorial)
13Occupational toxicology.(Lecture)
1312th Quiz Theo practical +OSPE.(Tutorial)
14Mutagenicity and carcinogenesis.(Lecture)
14Theoretical Presentations I .(Tutorial)
15Genetic and developmental toxicology.(Lecture)
15Theoretical Presentations II.(Tutorial)

Markets and Career

  • Generation, transmission, distribution and utilization of electrical power for public and private sectors to secure both continuous and emergency demands.
  • Electrical power feeding for civil and military marine and aviation utilities.
  • Electrical works in construction engineering.

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